叶柏华课题组介绍
导师介绍 |
|
研究方向 |
课题组研究方向包括新型药物设计与合成、大宗化学品转化、有机催化工业化、聚合物合成与降解。具体为通过研发新型化学键官能团化为核心,运用各种有机催化与不对称合成策略,借此建立高效催化体系,进而提供解决生命健康相关挑战与绿色能源转化的新思路。
其中研究内容包括:
✅ 亲电交叉偶联(XEC)合成药物 ✅ 过渡金属有机协同催化
✅ 新型手性配体设计与合成制备 ✅ 过渡金属催化相关DFT理论计算
✅ 多肽分子修饰 ✅ 能源物质绿色转化 ✅ 功能聚合物设计与制备
研究工作 |
[13] Jian-Tao Tang§, Yu Gan§, Xuejiao Li§, Baihua Ye* Chem 2022, in press§contributed equally “Regioselective reductive transamination of peptidic amides enabled by a dual Zr(IV)-H catalysis” https://doi.org/10.1016/j.chempr.2022.11.002 “Zirconium Catalysis” 研究方向:有机Zr-H催化 [12] book chapter entitled Hydrometallation of Organometallic Complexes; Jie Zhao*, Baihua Ye* Comprehensive Organometallic Chemistry IV, 2022 章节内容:过渡金属催化 [11] Ting-Feng Wu§, Yue-Jiao Zhang§, Yue Fu§, Fang-Jie Liu, Jian-Tao Tang, Peng Liu,* F. Dean Toste,* Baihua Ye* Chem 2021, 7, 1963-1974. §contributed equally “Zirconium-redox-shuttled cross-electrophile coupling of aromatic and heteroaromatic halides” 研究方向:亲电交叉偶联催化 XEC Chem & Chem Catalysis编辑精选 (https://mp.weixin.qq.com/s/xQCwR0eDq81seo_SqJjtqw) ShanghaiTech公众号报道(https://www.shanghaitech.edu.cn/2021/0714/c1001a67866/page.htm) [10] Baihua Ye§, Jie Zhao§, Ke Zhao, Jeffrey M. McKenna, F. Dean Toste* J. Am. Chem. Soc. 2018, 140, 8350-8356. §contributed equally “Chiral Diaryliodonium Phosphate Enables Light Driven Diastereoselective a-C(sp3)-H Acetalization” [9] Jie Zhao§, Son C. Nguyen§, Rong Ye§, Baihua Ye§, Horst Weller, Gabor A. Somorjai*, A. Paul Alivisatos*, F. Dean Toste* ACS Cent. Sci. 2017, 3, 482-488. §contributed equally 'A Comparison of Photocatalytic Activities of Gold Nanoparticles Following Plasmonic and Interband Excitation and a Strategy for Harnessing Interband Hot Carriers for Solution Phase Photocatalysis' [8] Baihua Ye, Nicolai Cramer* Acc. Chem. Res. 2015, 48, 1308-1318. “Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C-H Functionalizations” [7] Baihua Ye, Nicolai Cramer* Synlett 2015, 26, 1490-1495. “Chiral Cyclopentadienyl Ligands Enable a Rhodium(III)-Catalyzed Enantioselective Access to Hydroxychromames and Phthalides” [6] Matthew D. Wodrich§, Baihua Ye§, Jérôme. F. Gonthier, Clémence Corminboeuf, Nicolai Cramer* Chem. Eur. J. 2014, 20, 15409-15418. §contributed equally “Ligand-Controlled Regiodivergent Pathways of Rhodium(III)-Catalyzed Dihydroisoquinolone Synthesis: Experimental and Computational Studies of Different Cyclopentadienyl Ligands” [5] Baihua Ye, Nicolai Cramer* Angew. Chem. Int. Ed. 2014, 53, 7896-7899. “Asymmetric Synthesis of Isoindolones by Chiral Cyclopentadienyl-Rhodium(III)-Catalyzed C-H Functionalizations” [4] Baihua Ye, Pavel A. Donets, Nicolai Cramer* Angew. Chem. Int. Ed. 2014, 53, 507-511. “Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenesˮ [3]Baihua Ye, Nicolai Cramer* J. Am. Chem. Soc. 2013, 135, 636-639. “A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C-H Allylations of Benzamidesˮ [2]Baihua Ye, Nicolai Cramer* Science 2012, 338, 504-506. “Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalizationˮ [1] Manh V. Pham, Baihua Ye, Nicolai Cramer, Angew. Chem. Int. Ed. 2012, 51, 10610-10614. “Access to Sultams by Rhodium(III)-Catalyzed Directed C-H Activationsˮ |
课题组 |
汤健涛 博士生 | 吴庭峰 博士生 | 李雪娇 博士生 | |||
干宇 研究生 | 周俊锋 研究生 | 刘方杰 研究生 | |||
郭萍 研究生 | position available | 新成员 研究生 | position available | 新成员 研究生 |